Ipamorelin 5 mg — Growth Hormone Secretagogue

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Ipamorelin 5 mg — Growth Hormone Secretagogue

Ipamorelin 5 mg — Growth Hormone Secretagogue

Original price was: R999,99.Current price is: R649,99.

Ipamorelin is a highly selective Growth Hormone Secretagogue (GHS) that targets the ghrelin receptor (GHS-R1a) to promote controlled, pulse-like growth hormone (GH) release in research models. Because of its precision and minimal off-target impact, Ipamorelin is widely used to explore metabolic regulation, recovery dynamics, and sleep-linked endocrine rhythms in a laboratory setting.

Within controlled environments, Ipamorelin is valued for its clean profile: low effect on cortisol and prolactin, stable GH-axis activation, and strong compatibility with synergistic peptides such as CJC-1295 and Sermorelin.

Key Themes

  • Stable GH-axis activation with repeatable pulse amplitude.
  • Explored in models assessing soft-tissue repair and post-exercise recovery markers.
  • Investigated for potential influence on body composition and appetite signalling.
  • Studied in relation to sleep architecture and night-time endocrine response patterns.
  • Demonstrates enhanced GH pulsatility when paired with GHRH analogues such as CJC-1295 or Sermorelin, allowing combined GHRH/GHRP modelling.
  • Minimal impact on cortisol and prolactin in many models, making it a preferred candidate for “clean” GH stimulation studies.
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Description

Mechanism of Action & Research Findings

Ipamorelin exerts its primary effect by binding selectively to the ghrelin receptor (GHS-R1a). This receptor engagement initiates a signalling cascade that triggers pulsatile GH release from the anterior pituitary, mimicking physiologic secretion patterns without notable stimulation of ACTH or prolactin.

What’s in the Box

  • 1 × Ipamorelin 5 mg pre-reconstituted in 2 mL bacteriostatic water (pen-system compatible)
  • 1 × replacement needle

Dosage Protocol — Pen System)

The Clinic standardises all cartridges to simplify research use and improve dose reproducibility.

  • Pen volume: 3 mL
  • Total clicks per pen: 300 clicks
  • Ipamorelin content per cartridge: 5 mg
  • Calculated strength: 5000 mcg ÷ 300 clicks = 17mcg per click
  • Minimum mid-point dose: 10 clicks (250 mcg)

Suggested Dosing

Standard Dose

3 times per day

Clicks Dose (mcg)
6 clicks 100 mcg
9 clicks 150 mcg


Pen lasts for: 11 to 17 days

Advanced Dose

3 times per day

Clicks Dose (mcg)
15 clicks 250 mcg
18 clicks 300 mcg


Pen lasts for: 6 to 7 days

Frequency & Cycle Length

  • Frequency: 2–3 subcutaneous events per day (e.g. AM fasted and/or pre-sleep), depending on study design.
  • Cycle length: 8–12 weeks is typically used for meaningful GH-pulse modelling.

Expected Outcomes

Ipamorelin has been associated with:

  • Increased frequency and amplitude of GH pulsatility.
  • Supportive data for improved tissue repair and post-exercise recovery markers.
  • Potential shifts in body-composition parameters under specific protocols.
  • Interaction with sleep architecture and night-time GH release patterns.
  • Enhanced GH response when combined with CJC-1295 or Sermorelin.

All outcomes remain dependent on model, protocol, and research conditions, and should not be interpreted as therapeutic claims.

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